GE2270
naturalproductmech:mibig-47e25f64fe MINTED SEEDED
Structure
| Standard InChIKey | YMUAOVHRCGSGJV-UHFFFAOYSA-N |
|---|---|
| SMILES | CC1=C2C(=O)NCC(=O)NC(C3=NC(=CS3)C4=NC(=CS4)C5=C(C=CC(=N5)C6=NC(=CS6)C7=NC(CO7)C(=O)N8CCCC8C(=O)N)C9=NC(=CS9)C(=O)NC(C3=NC(=C(S3)COC)C(=O)NC(C(=N2)S1)CC(=O)NC)C(C)C)C(C1=CC=CC=C1)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:16130335 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Nonomuraea sp. WU8817 NCBITaxon:653884 |
BGC_CHARACTERIZED | mibig:BGC0000604 | PMID:19338336 |
| Planobispora rosea NCBITaxon:35762 |
BGC_CHARACTERIZED | mibig:BGC0001155 | DOI:10.7164/antibiotics.44.693 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Planobispora rosea NCBITaxon:35762 |
LOTUS | DOI:10.7164/ANTIBIOTICS.44.693 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000604 | Nonomuraea sp. WU8817 NCBITaxon:653884 |
CLUSTER_DEMONSTRATED | genbank:FJ461359.1 |
| mibig:BGC0001155 | Planobispora rosea NCBITaxon:35762 |
CLUSTER_DEMONSTRATED | genbank:KF366381.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000604, BGC0001155. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000604 | MIBIG | 4 |
| BGC0001155 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/ge2270.yaml, which is generated from the committed inventories. Neither is edited by hand.