NaturalProductMech

gramicidin

naturalproductmech:mibig-eea3f40592 MINTED SEEDED antibacterial

Structure

Standard InChIKeyZWCXYZRRTRDGQE-SORVKSEFSA-N
SMILESC[C@@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC7=CNC8=CC=CC=C87)C(=O)NCCO)NC(=O)CNC(=O)[C@H](C(C)C)NC=O
Stereochemistryfully defined
Cross-referencespubchem:16130140

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Brevibacillus brevis NBRC 100599
NCBITaxon:358681
SOURCE_ASSERTION mibig:BGC0000367 PMID:23144389

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Brevibacillus brevis
NCBITaxon:1393
LOTUS DOI:10.1128/JB.01312-12

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000367 Brevibacillus brevis NBRC 100599
NCBITaxon:358681
CLUSTER_UNSTATED genbank:AP008955.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0000367MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/gramicidin.yaml, which is generated from the committed inventories. Neither is edited by hand.