group 1 methanobactin
naturalproductmech:mibig-2d49c2c4bf MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | XOADWJQVJWCREC-DZHAIUNBSA-N |
|---|---|
| SMILES | CSCC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)SC2=C(O)[NH]C(C(=O)OC(C)C)=N2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N2CCCC2C2=NC(O)=C([NH]2)C(=S)N[C@@H](CO)C(=O)N1)C(=O)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA033449, pubchem:135659045 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 3
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Methylosinus sp. LW4 NCBITaxon:136993 |
BGC_CORRELATED | mibig:BGC0002132 | PMID:27527063 |
| Methylosinus trichosporium OB3b NCBITaxon:595536 |
SOURCE_ASSERTION | mibig:BGC0002004 | DOI:10.2991/meici-15.2015.56 |
| Methylosinus sp. LW3 NCBITaxon:107635 |
SOURCE_ASSERTION | mibig:BGC0002133 | PMID:34510894 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Methylosinus trichosporium NCBITaxon:426 |
LOTUS | DOI:10.1126/SCIENCE.1098322 |
Biosynthetic gene clusters 3
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002132 | Methylosinus sp. LW4 NCBITaxon:136993 |
CLUSTER_CORRELATED | genbank:NZ_KB900627.1 |
| mibig:BGC0002004 | Methylosinus trichosporium OB3b NCBITaxon:595536 |
CLUSTER_UNSTATED | genbank:NZ_CP023737.1 |
| mibig:BGC0002133 | Methylosinus sp. LW3 NCBITaxon:107635 |
CLUSTER_UNSTATED | genbank:NZ_AZUO01000002.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0002004, BGC0002132, BGC0002133. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002132 | MIBIG | 3 |
| BGC0002004 | MIBIG | 3 |
| BGC0002133 | MIBIG | 3 |
This page is generated from data/natural_products/amino_acids_and_peptides/group-1-methanobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.