NaturalProductMech

group 1 methanobactin

naturalproductmech:mibig-2d49c2c4bf MINTED SEEDED

Structure

Standard InChIKeyXOADWJQVJWCREC-DZHAIUNBSA-N
SMILESCSCC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)SC2=C(O)[NH]C(C(=O)OC(C)C)=N2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N2CCCC2C2=NC(O)=C([NH]2)C(=S)N[C@@H](CO)C(=O)N1)C(=O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA033449, pubchem:135659045

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Methylosinus sp. LW4
NCBITaxon:136993
BGC_CORRELATED mibig:BGC0002132 PMID:27527063
Methylosinus trichosporium OB3b
NCBITaxon:595536
SOURCE_ASSERTION mibig:BGC0002004 DOI:10.2991/meici-15.2015.56
Methylosinus sp. LW3
NCBITaxon:107635
SOURCE_ASSERTION mibig:BGC0002133 PMID:34510894

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Methylosinus trichosporium
NCBITaxon:426
LOTUS DOI:10.1126/SCIENCE.1098322

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0002132 Methylosinus sp. LW4
NCBITaxon:136993
CLUSTER_CORRELATED genbank:NZ_KB900627.1
mibig:BGC0002004 Methylosinus trichosporium OB3b
NCBITaxon:595536
CLUSTER_UNSTATED genbank:NZ_CP023737.1
mibig:BGC0002133 Methylosinus sp. LW3
NCBITaxon:107635
CLUSTER_UNSTATED genbank:NZ_AZUO01000002.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002004, BGC0002132, BGC0002133. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002132MIBIG3
BGC0002004MIBIG3
BGC0002133MIBIG3

This page is generated from data/natural_products/amino_acids_and_peptides/group-1-methanobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.