isodomoic acid A
CHEBI:176782 EXACT SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
An L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,5-dien-2-yl group at position 4. It is isolated from the red alga, Chondria armata.
Structure
| Standard InChIKey | DDAJBUQQWFXHDM-UUYKTWPLSA-N |
|---|---|
| SMILES | OC(/C(C)=C/C/C=C([C@@]1([H])CN[C@H](C(O)=O)[C@H]1CC(O)=O)/C)=O |
| Stereochemistry | fully defined |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Chondria armata NCBITaxon:860625 |
SOURCE_ASSERTION | mibig:BGC0002644 | DOI:10.1073/pnas.2117407119 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Chondria armata NCBITaxon:860625 |
LOTUS | DOI:10.1016/S0041-0101(96)00123-7 |
| Chondria armata NCBITaxon:860625 |
LOTUS | DOI:10.1248/CPB.34.4892 |
| Chondria armata NCBITaxon:860625 |
CHEBI | PMID:29321590 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002644 | Chondria armata NCBITaxon:860625 |
CLUSTER_DEMONSTRATED | genbank:OK169902.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002644 | MIBIG | 2 |
| CHEBI:176782 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/isodomoic-acid-a.yaml, which is generated from the committed inventories. Neither is edited by hand.