isopenicillin N
CHEBI:18165 EXACT SEEDED antimicrobial unspecified
Structure
| Standard InChIKey | MIFYHUACUWQUKT-GTQWGBSQSA-N |
|---|---|
| SMILES | [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)CCC[C@H](N)C(O)=O)C(O)=O |
| Stereochemistry | fully defined |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium chrysogenum NCBITaxon:5076 |
SOURCE_ASSERTION | mibig:BGC0000405 | PMID:1368505 |
Occurrences 17
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1007/BF01570004 |
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1111/J.1365-2958.2005.04581.X |
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1128/JB.175.3.623-629.1993 |
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1515/ZNC-2001-9-1020 |
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.7164/ANTIBIOTICS.35.483 |
| Flavobacterium NCBITaxon:237 |
LOTUS | DOI:10.1007/BF00428576 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1038/318191A0 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1039/C39830001317 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1039/C39830001319 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1039/C39840001225 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1039/C39860000110 |
| Cephalosporium acremonium NCBITaxon:5044 |
LOTUS | DOI:10.1039/P19850000369 |
| Sarocladium strictum NCBITaxon:5046 |
LOTUS | DOI:10.1039/C39830001317 |
| Sarocladium strictum NCBITaxon:5046 |
LOTUS | DOI:10.1039/C39830001319 |
| Sarocladium strictum NCBITaxon:5046 |
LOTUS | DOI:10.1039/C39840001225 |
| Sarocladium strictum NCBITaxon:5046 |
LOTUS | DOI:10.1039/C39860000110 |
| Sarocladium strictum NCBITaxon:5046 |
LOTUS | DOI:10.1039/P19850000369 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000405 | Penicillium chrysogenum NCBITaxon:5076 |
CLUSTER_DEMONSTRATED | genbank:EF601124.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:18165 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000405 | MIBIG | 5 |
| CHEBI:18165 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/isopenicillin-n.yaml, which is generated from the committed inventories. Neither is edited by hand.