kasumigamide
naturalproductmech:mibig-bad5822c6e MINTED SEEDED
Structure
| Standard InChIKey | WUXSZVRSSSITPJ-LHXUXNRLSA-N |
|---|---|
| SMILES | NC(=N)NCCC[C@@H](NC(=O)C[C@H](O)[C@@H](CC1=CNC2=CC=CC=C12)NC(=O)CCNC(=O)[C@H](O)CC1=CC=CC=C1)C(=O)N[C@H]([C@H](O)C1=CC=CC=C1)C(O)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA0355 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| uncultured Candidatus Entotheonella sp. NCBITaxon:312019 |
SOURCE_ASSERTION | mibig:BGC0001630 | PMID:27732651 |
| Microcystis aeruginosa NIES-87 NCBITaxon:449440 |
SOURCE_ASSERTION | mibig:BGC0001631 | PMID:27732651 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Microcystis aeruginosa NCBITaxon:1126 |
LOTUS | DOI:10.1021/JO991918F |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001630 | uncultured Candidatus Entotheonella sp. NCBITaxon:312019 |
CLUSTER_UNSTATED | genbank:LC160290.1 |
| mibig:BGC0001631 | Microcystis aeruginosa NIES-87 NCBITaxon:449440 |
CLUSTER_UNSTATED | genbank:LC160291.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001630, BGC0001631. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001630 | MIBIG | 4 |
| BGC0001631 | MIBIG | 4 |
This page is generated from data/natural_products/amino_acids_and_peptides/kasumigamide.yaml, which is generated from the committed inventories. Neither is edited by hand.