lacticin 481
naturalproductmech:mibig-723ce15f16 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | VIEVUPYQRUJFFA-XFKIZFQISA-N |
|---|---|
| SMILES | CCC(C)C(NC(=O)C(NC(=O)CNC(=O)C(CO)NC(=O)CNC(=O)CNC(=O)C(N)CCCCN)C(C)C)C(=O)NC(CC1=CNC=N1)C(=O)NC1C(C)SCC2NC(=O)C(CCC(O)=O)NC(=O)C(CC3=CNC=N3)NC(=O)C(CSCC3NC(=O)\C(NC(=O)C(CC4=CC=CC=C4)NC(=O)C(NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CCC(N)=O)NC(=O)C(CC4=CNC5=C4C=CC=C5)NC(=O)C(CSCC(NC3=O)C(=O)NC(CO)C(O)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC(=O)C(CC(N)=O)NC2=O)C(C)C)=C\C)NC(=O)C(NC1=O)C(C)CC |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA015244 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Lactococcus lactis subsp. lactis NCBITaxon:1360 |
SOURCE_ASSERTION | mibig:BGC0000521 | PMID:8017945 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Lactococcus NCBITaxon:1357 |
LOTUS | DOI:10.1016/0014-5793(96)00771-5 |
| Lactococcus lactis NCBITaxon:1358 |
LOTUS | DOI:10.1016/0014-5793(96)00771-5 |
| Lactococcus lactis NCBITaxon:1358 |
LOTUS | DOI:10.1128/AEM.58.1.279-284.1992 |
| Lactococcus lactis NCBITaxon:1358 |
LOTUS | DOI:10.1128/AEM.62.5.1799-1802.1996 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000521 | Lactococcus lactis subsp. lactis NCBITaxon:1360 |
CLUSTER_UNSTATED | genbank:U91581.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000521 | MIBIG | 3 |
This page is generated from data/natural_products/amino_acids_and_peptides/lacticin-481.yaml, which is generated from the committed inventories. Neither is edited by hand.