NaturalProductMech

lactocillin

naturalproductmech:mibig-54a8c938bd MINTED SEEDED

Structure

Standard InChIKeyWTPCCOAKKCTBIB-PLYROHNOSA-N
SMILESO=C(NC(C(O)=O)C)C1=CSC(C2=CSC(C3=NC(C4=CSC(C(CSC(C5=CNC6=C5C=CC=C6)=O)NC7=O)=N4)=C(C8=NC(C(NC(C(C)O)C(N/C(C9=NC(C(NC(C%10=NC7CS%10)C(O)C)=O)=CS9)=C\C)=O)=O)=CS8)C=C3)=N2)=N1
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Lactobacillus paragasseri JV-V03
NCBITaxon:525326
BGC_CHARACTERIZED mibig:BGC0000628 PMID:25215495

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000628 Lactobacillus paragasseri JV-V03
NCBITaxon:525326
CLUSTER_DEMONSTRATED genbank:ACGO02000004.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000628MIBIG4

This page is generated from data/natural_products/amino_acids_and_peptides/lactocillin.yaml, which is generated from the committed inventories. Neither is edited by hand.