Leepeptin
naturalproductmech:mibig-e6b8bf6abd MINTED SEEDED
Structure
| Standard InChIKey | UDBDQVQDKZANRU-GYZZVETDSA-N |
|---|---|
| SMILES | CC[C@H](C)C(NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)NC(C(=O)O)[C@@H](C)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA027201 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces leeuwenhoekii NCBITaxon:1437453 |
SOURCE_ASSERTION | mibig:BGC0002289 | DOI:10.1128/aem.01752-19 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces leeuwenhoekii NCBITaxon:1437453 |
LOTUS | DOI:10.1128/AEM.01752-19 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002289 | Streptomyces leeuwenhoekii NCBITaxon:1437453 |
CLUSTER_DEMONSTRATED | genbank:LN831790.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002289 | MIBIG | 2 |
This page is generated from data/natural_products/amino_acids_and_peptides/leepeptin.yaml, which is generated from the committed inventories. Neither is edited by hand.