leupeptin Pr
naturalproductmech:mibig-d7a4b8261a MINTED SEEDED
Structure
| Standard InChIKey | BFUKWVVFVGUARP-BSOSBYQFSA-N |
|---|---|
| SMILES | CCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NC(CCCN=C(N)N)C=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA013087 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces roseus NCBITaxon:66430 |
BGC_CHARACTERIZED | mibig:BGC0002095 | DOI:10.1101/2020.10.26.356543 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces roseus NCBITaxon:66430 |
LOTUS | DOI:10.1101/2020.10.26.356543 |
| Streptomyces roseus NCBITaxon:66430 |
LOTUS | DOI:10.1248/CPB.17.1896 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002095 | Streptomyces roseus NCBITaxon:66430 |
CLUSTER_DEMONSTRATED | genbank:LFML01000163.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002095 | MIBIG | 3 |
This page is generated from data/natural_products/amino_acids_and_peptides/leupeptin-pr.yaml, which is generated from the committed inventories. Neither is edited by hand.