NaturalProductMech

microcin J25

naturalproductmech:mibig-c68748ca1b MINTED SEEDED

Structure

Standard InChIKeyFRJVEVHOMWPHHN-UHFFFAOYSA-N
SMILESCCC(C)C(C(=O)NCC(=O)NC(C(C)O)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NCC(=O)O)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C6CCC(=O)NCC(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N7CCCC7C(=O)N6)C(C)C)CC8=CN=CN8)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:57397977, npatlas:NPA05946

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Escherichia coli AY25
NCBITaxon:562
SOURCE_ASSERTION mibig:BGC0000581 DOI:10.1128/jb.178.12.3661-3663.1996

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000581 Escherichia coli AY25
NCBITaxon:562
CLUSTER_DEMONSTRATED genbank:AF061787.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000581MIBIG6

This page is generated from data/natural_products/amino_acids_and_peptides/microcin-j25.yaml, which is generated from the committed inventories. Neither is edited by hand.