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microcyclamide

naturalproductmech:mibig-33d65bf6bd MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyVJNFZONNMHDIHW-DYIBVVGTSA-N
SMILESCC[C@H](C)[C@H]1C2=NC(=CS2)C(=O)N[C@H](C3=NC(=CS3)C(=O)N[C@H](C4=NC(=C(O4)C)C(=O)N1)C)CC5=CN=CN5C
Stereochemistryfully defined
Cross-referencespubchem:10555282

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Microcystis aeruginosa PCC 7806
NCBITaxon:267872
SOURCE_ASSERTION mibig:BGC0000474 PMID:18245249

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Microcystis aeruginosa
NCBITaxon:1126
LOTUS DOI:10.1016/S0031-9422(97)00943-6
Microcystis aeruginosa
NCBITaxon:1126
LOTUS DOI:10.1021/NP000159P
Microcystis aeruginosa
NCBITaxon:1126
LOTUS DOI:10.1021/NP800631T
Microcystis aeruginosa
NCBITaxon:1126
LOTUS DOI:10.1021/NP970146K
Microcystis aeruginosa
NCBITaxon:1126
LOTUS DOI:10.1128/AEM.02392-07
Microcystis aeruginosa
NCBITaxon:1126
CYANOMETDB PMID:11000050

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000474 Microcystis aeruginosa PCC 7806
NCBITaxon:267872
CLUSTER_UNSTATED genbank:AM931579.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (0 causal) 6 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT microcyclamide naturalproductmech:mibig-33d65bf6bd Amino acids and peptides TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

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Provenance

Source conceptSourceVersion
BGC0000474MIBIG4

This page is generated from data/natural_products/amino_acids_and_peptides/microcyclamide.yaml, which is generated from the committed inventories. Neither is edited by hand.