N-acetyltryptophan
CHEBI:70976 EXACT SEEDED
An N-acetylamino acid that is the N-acetyl derivative of tryptophan.
Structure
| Standard InChIKey | DZTHIGRZJZPRDV-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(=O)NC(CC1=CNC2=C1C=CC=C2)C(O)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA015473 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
SOURCE_ASSERTION | mibig:BGC0001679 | DOI:10.1038/s41598-021-88693-8 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Bacillus pumilus NCBITaxon:1408 |
LOTUS | DOI:10.1016/S0378-1097(02)01065-0 |
| Aspergillus nidulans NCBITaxon:162425 |
LOTUS | DOI:10.1016/J.FGB.2017.01.006 |
| Penicillium commune NCBITaxon:36653 |
LOTUS | DOI:10.3390/MOLECULES15053270 |
| Glycine max NCBITaxon:3847 |
LOTUS | DOI:10.1111/TPJ.12607 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001679 | Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
CLUSTER_UNSTATED | genbank:BN001303.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Molecular targets 1
| Target | Assay organism | Measurement | Reference |
|---|---|---|---|
| Tryptophanase UniProtKB:P0A853 |
Escherichia coli (strain K12) NCBITaxon:83333 |
KI 4.8e+07 nM | PMID:18608755 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001679 | MIBIG | 3 |
| CHEBI:70976 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/n-acetyltryptophan.yaml, which is generated from the committed inventories. Neither is edited by hand.