nocathiacin I
naturalproductmech:mibig-566cdea0b9 MINTED SEEDED
Structure
| Standard InChIKey | FFLJEMWVYVKPDW-UMNFMQIXSA-N |
|---|---|
| SMILES | C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@H]2[C@@H]3[C@H]4C5=NC(=CS5)C(=O)N[C@@H](COC(=O)C6=C(CO3)C7=C(COC2=O)C=CC=C7N6O)C8=NC(=CS8)C9=NC(=C(C=C9C1=NC(=CS1)C(=O)N[C@H](C(=O)N/C(=C(\C)/OC)/C1=NC(=CS1)C(=O)N4)[C@@H](C)O)O)C1=NC(=CS1)C(=O)NC(=C)C(=O)N)(C)O)N(C)C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA016398 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Actinokineospora fastidiosa NCBITaxon:1816 |
SOURCE_ASSERTION | mibig:BGC0000608 | DOI:10.7164/antibiotics.56.232 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nocardia NCBITaxon:1817 |
LOTUS | DOI:10.7164/ANTIBIOTICS.56.226 |
| Actinokineospora fastidiosa NCBITaxon:1816 |
LOTUS | DOI:10.1021/NP800783B |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000608 | Actinokineospora fastidiosa NCBITaxon:1816 |
CLUSTER_UNSTATED | genbank:HM236314.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000608 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/nocathiacin-i.yaml, which is generated from the committed inventories. Neither is edited by hand.