NaturalProductMech

nocathioamide A

naturalproductmech:mibig-62a15176ec MINTED SEEDED

Structure

Standard InChIKeyCODBWSAIQSAFCS-MYZGCEDNSA-N
SMILESC=C1NC(=O)C2CSCC3NC(=O)C(CSC(C)C(NC(=S)C(CC4=CN=C[NH]4)NC(=O)C4=CSC(C(C)NC(C)=O)=N4)C(=O)N[C@@H](CC(C)C(=O)NC(=O)CC(C(=O)O)NC(=O)C(C)NC3=O)C(=O)N2)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CC(C)C)NC1=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA033270

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Nocardia terpenica IFM 0706
NCBITaxon:455432
SOURCE_ASSERTION mibig:BGC0002120 PMID:32816977

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Nocardia terpenica
NCBITaxon:455432
LOTUS DOI:10.1128/MRA.00689-20

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002120 Nocardia terpenica IFM 0706
NCBITaxon:455432
CLUSTER_UNSTATED genbank:JABMCZ010000005.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002120MIBIG3

This page is generated from data/natural_products/amino_acids_and_peptides/nocathioamide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.