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patellamide B

naturalproductmech:mibig-18c1dde7bd MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyFDAPKNJHIHKHDM-XGKKPBRYSA-N
SMILESCC[C@H](C)[C@H]1C2=N[C@@H]([C@H](O2)C)C(=O)N[C@@H](C3=NC(=CS3)C(=O)N[C@H](C4=N[C@@H]([C@H](O4)C)C(=O)N[C@@H](C5=NC(=CS5)C(=O)N1)C)CC(C)C)CC6=CC=CC=C6
Stereochemistryfully defined

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
uncultured Prochloron sp.
NCBITaxon:259942
BGC_CORRELATED mibig:BGC0000476 PMID:17086177

Occurrences 13

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Prochloron
NCBITaxon:1214
LOTUS DOI:10.1021/JO00349A002
Prochloron
NCBITaxon:1214
LOTUS DOI:10.1021/NP049948N
Prochloron
NCBITaxon:1214
LOTUS DOI:10.1038/NCHEMBIO.84
Prochloron sp.
NCBITaxon:1215
CYANOMETDB DOI:10.1021/jo00349a002
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1007/BF02969512
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1016/S0040-4039(00)98736-7
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/JO00043A017
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/JO00172A001
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/NP010556F
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/NP50064A011
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/NP50081A016
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/NP50118A020
Lissoclinum patella
NCBITaxon:13110
LOTUS DOI:10.1021/NP9802872

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000476 uncultured Prochloron sp.
NCBITaxon:259942
CLUSTER_CORRELATED genbank:DQ869558.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (0 causal) 13 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT patellamide B naturalproductmech:mibig-18c1dde7bd Amino acids and peptides TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

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Provenance

Source conceptSourceVersion
BGC0000476MIBIG3

This page is generated from data/natural_products/amino_acids_and_peptides/patellamide-b.yaml, which is generated from the committed inventories. Neither is edited by hand.