pneumocandin A0
naturalproductmech:mibig-ceef0c01d9 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | DFQUSLQYURJBIT-GNDCHVOXSA-N |
|---|---|
| SMILES | [H][C@@]12C[C@@H](O)CN1C(=O)[C@@]([H])(NC(=O)[C@@H](C[C@@H](O)[C@@H](O)NC(=O)[C@]1([H])[C@@H](O)[C@@H](C)CN1C(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@H](O)[C@@H](O)C1=CC=C(O)C=C1)[C@H](O)CC(N)=O)NC(=O)CCCCCCCC[C@@H](C)C[C@@H](C)CC)[C@@H](C)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA01123, pubchem:456419 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Glarea lozoyensis ATCC 20868 NCBITaxon:1116229 |
BGC_CHARACTERIZED | mibig:BGC0001035 | PMID:23688303 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Glarea lozoyensis NCBITaxon:101852 |
LOTUS | DOI:10.1016/S0953-7562(09)80401-2 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001035 | Glarea lozoyensis ATCC 20868 NCBITaxon:1116229 |
CLUSTER_DEMONSTRATED | genbank:KE145356.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001035 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/pneumocandin-a0.yaml, which is generated from the committed inventories. Neither is edited by hand.