polymyxin B
naturalproductmech:mibig-8a23419be1 MINTED SEEDED
Structure
| Standard InChIKey | WQVJHHACXVLGBL-NARAKGNPSA-N |
|---|---|
| SMILES | CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)[C@@H](C)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:9833652 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Paenibacillus polymyxa NCBITaxon:1406 |
BGC_CHARACTERIZED | mibig:BGC0001153 | PMID:22195566 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/ACS.JNATPROD.8B00544 |
| Paenibacillus polymyxa NCBITaxon:1406 |
LOTUS | DOI:10.1016/J.CHEMBIOL.2011.09.017 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001153 | Paenibacillus polymyxa NCBITaxon:1406 |
CLUSTER_DEMONSTRATED | genbank:JN660148.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001153 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/polymyxin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.