NaturalProductMech

ristomycin A

naturalproductmech:mibig-7a0a19126a MINTED SEEDED

Structure

Standard InChIKeyVUOPFFVAZTUEGW-UHFFFAOYSA-N
SMILESCC1C(C(CC(O1)OC2C3C(=O)NC(C4=CC(=CC(=C4C5=C(C=CC(=C5)C(C(=O)N3)NC(=O)C6C7=CC(=C(C(=C7)OC8=CC=C2C=C8)OC9C(C(C(C(O9)COC1C(C(C(C(O1)C)O)O)O)O)O)OC1C(C(C(C(O1)CO)O)O)OC1C(C(C(CO1)O)O)O)OC1=CC=C(C=C1)C(C1C(=O)NC(C2=CC(=C(C(=C2)O)C)OC2=C(C=CC(=C2)C(C(=O)N1)N)O)C(=O)N6)O)O)OC1C(C(C(C(O1)CO)O)O)O)O)C(=O)OC)N)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:16131418

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, saccharide, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Amycolatopsis japonica
NCBITaxon:208439
BGC_CORRELATED mibig:BGC0000419 PMID:25114137

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Amycolatopsis lurida
NCBITaxon:31959
LOTUS DOI:10.1128/AAC.03349-14
Amycolatopsis lurida
NCBITaxon:31959
LOTUS DOI:10.1128/GENOMEA.01050-14
Amycolatopsis japonica
NCBITaxon:208439
LOTUS DOI:10.1128/AAC.03512-14

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000419 Amycolatopsis japonica
NCBITaxon:208439
CLUSTER_CORRELATED genbank:CP008953.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000419MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/ristomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.