SapB

naturalproductmech:mibig-d4920f88ae MINTED SEEDED

Structure

Standard InChIKey	BBIKPGRUAMIMIA-UHFFFAOYSA-N
SMILES	CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSCC(C(=O)NC(C(=O)NC(C(=O)NC(=C)C(=O)N1)CC(C)C)CO)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C2CSCC(C(=O)NC(C(=O)NC(C(=O)NC(=C)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(C)C)CC(C)C)CC(C)C)C)CCCNC(=N)N)NC(=O)CNC(=O)C(C(C)O)N)C(=O)NC(CC(=O)N)C(=O)O)C(C)O)C(C)O
Stereochemistry	undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Streptomyces coelicolor A3(2) NCBITaxon:100226	BGC_CORRELATED	mibig:BGC0000551	PMID:15277670

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Streptomyces albidoflavus NCBITaxon:1886	LOTUS	DOI:10.1073/PNAS.0404220101
Streptomyces coelicolor NCBITaxon:1902	LOTUS	DOI:10.1073/PNAS.0404220101

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0000551	Streptomyces coelicolor A3(2) NCBITaxon:100226	CLUSTER_CORRELATED	genbank:AL645882.2

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source concept	Source	Version
BGC0000551	MIBIG	5

This page is generated from data/natural_products/amino_acids_and_peptides/sapb.yaml, which is generated from the committed inventories. Neither is edited by hand.