NaturalProductMech

siomycin A

naturalproductmech:mibig-71aa61cfbb MINTED SEEDED

Structure

Standard InChIKeyAKFVOKPQHFBYCA-UHFFFAOYSA-N
SMILESCC=C1C2=NC(CS2)C(=O)NC(C3=NC(=CS3)C(=O)NC4C(OC(=O)C5=NC6=C(C=CC(C6O)NC(C(=O)NC(=C)C(=O)NC(=C)C(=O)NC(C(=O)NC7(CCC(=NC7C8=CSC4=N8)C9=NC(=CS9)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)C2=NC(=CS2)C(=O)NC(C(=O)N1)C(C)O)C)C(C)C)C(=C5)C(C)O)C)C(C)(C(C)O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:16130049

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sioyaensis
NCBITaxon:67364
SOURCE_ASSERTION mibig:BGC0000611 PMID:19246004

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces sioyaensis
NCBITaxon:67364
LOTUS DOI:10.7164/ANTIBIOTICS.22.423

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000611 Streptomyces sioyaensis
NCBITaxon:67364
CLUSTER_UNSTATED genbank:FJ436355.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000611MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/siomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.