NaturalProductMech

staphyloferrin B

CHEBI:134612 EXACT SEEDED

A siderophore composed from L-2,3-diaminopropionic acid, citric acid, 1,2-diaminoethane and α-ketoglutaric acid units.

Structure

Standard InChIKeySIAZVTIHOHTZDD-PWJLMRLQSA-N
SMILESC(CC(=O)NCCNC(=O)C[C@](CC(=O)NC[C@@H](C(=O)O)N)(C(=O)O)O)C(=O)C(=O)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA012996

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Staphylococcus aureus subsp. aureus NCTC 8325
NCBITaxon:93061
SOURCE_ASSERTION mibig:BGC0000943 PMID:14688077

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Cupriavidus necator
NCBITaxon:106590
LOTUS DOI:10.1515/ZNC-1999-1103
Staphylococcus aureus
NCBITaxon:1280
CHEBI PMID:26030732
Staphylococcus hyicus
NCBITaxon:1284
LOTUS DOI:10.1016/0378-1097(94)90002-7
Staphylococcus hyicus
NCBITaxon:1284
CHEBI PMID:8138126

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000943 Staphylococcus aureus subsp. aureus NCTC 8325
NCBITaxon:93061
CLUSTER_DEMONSTRATED genbank:LS483365.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000943MIBIG5
CHEBI:134612CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/staphyloferrin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.