tallysomycin A
naturalproductmech:mibig-31266dfbb0 MINTED SEEDED cytotoxic
Structure
| Standard InChIKey | VUPBDWQPEOWRQP-UHFFFAOYSA-N |
|---|---|
| SMILES | CC1C(C(C(C(O1)OC(C(C2=NC(=CS2)C3=NC(=CS3)C(=O)NCCCC(CC(=O)NCCCNCCCCN)N)O)NC(=O)C(C(C)O)NC(=O)CC(C(C)NC(=O)C(C(C4=CN=CN4)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)OC(=O)N)O)NC(=O)C7=C(C(=NC(=N7)C(CC(=O)N)NCC(C(=O)N)N)N)C)O)O)O)N |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:430602 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptoalloteichus hindustanus NCBITaxon:2017 |
BGC_CHARACTERIZED | mibig:BGC0001048 | PMID:17216057 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptoalloteichus hindustanus NCBITaxon:2017 |
LOTUS | DOI:10.1039/B615284H |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001048 | Streptoalloteichus hindustanus NCBITaxon:2017 |
CLUSTER_DEMONSTRATED | genbank:EF032505.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| NCI In Vivo Anticancer Drug Screen. Data for tumor model B16 Melanoma (subcutaneous) in B6D2F1 (BDF1) mice | ACTIVE | pubchem.aid:194 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001048 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/tallysomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.