NaturalProductMech

theonellamide

naturalproductmech:mibig-0fb6b72d81 MINTED SEEDED

Structure

Standard InChIKeyWVJFAKMMDQFEDM-UZGFQBTNSA-N
SMILESC[C@H]([C@H]1C(=O)NC[C@@H](C(=O)N[C@@H](C[C@H](CC(=O)N[C@H]2CC3=CN(C[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)[C@H](C(=O)N)O)CC(=O)N)NC(=O)[C@@H](NC(=O)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@H](C)O)CO)CC4=CC=CC=C4)[C@H](/C=C(\C)/C=C/C5=CC=CC=C5)O)CO)C=[N+]3[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)CO)O)O)O)O)C(=O)[O-])O)C7=CC=C(C=C7)Br
Stereochemistryfully defined

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Candidatus Entotheonella serta
NCBITaxon:1652106
SOURCE_ASSERTION mibig:BGC0001800 PMID:29439203

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Theonella
NCBITaxon:37504
LOTUS DOI:10.1021/JO00110A020

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001800 Candidatus Entotheonella serta
NCBITaxon:1652106
CLUSTER_UNSTATED genbank:MG844357.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001800MIBIG4

This page is generated from data/natural_products/amino_acids_and_peptides/theonellamide.yaml, which is generated from the committed inventories. Neither is edited by hand.