thioholgamide B
naturalproductmech:mibig-4d42aab3e9 MINTED SEEDED
Structure
| Standard InChIKey | ZKVMUPABRRWKON-UHFFFAOYSA-O |
|---|---|
| SMILES | C(C(C)=O)(NC(C(C)C)C(NC(CCS(=O)C)C(NC(C(NC(C(NC(C(NC(C(NC1C(=O)NC(C(NC(C)C(=O)NC(CC2C=CC=CC=2)C(NC(C(O)C2N(C)C=[N+](C)C=2)C(=O)NC=CSC1C)=O)=O)C(C)C)=O)C)=S)C)=S)C)=O)C)=S)=S)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA013128 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces malaysiense NCBITaxon:1428626 |
SOURCE_ASSERTION | mibig:BGC0001802 | PMID:28981254 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces malaysiensis NCBITaxon:92644 |
LOTUS | DOI:10.1021/ACSCHEMBIO.7B00676 |
| Streptomyces malaysiense NCBITaxon:1428626 |
LOTUS | DOI:10.1021/ACSCHEMBIO.7B00676 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001802 | Streptomyces malaysiense NCBITaxon:1428626 |
CLUSTER_UNSTATED | genbank:MF593843.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001802 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/thioholgamide-b.yaml, which is generated from the committed inventories. Neither is edited by hand.