thiomuracin
naturalproductmech:mibig-c33fd38850 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | LXOSXNJTQRTDJG-IKGSVZLMSA-N |
|---|---|
| SMILES | O=C1C2=CSC(C3=C(C4=CSC(C5=CSC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)NC(C7=CSC([C@H]([C@H](O)C8=CC=CC=C8)NC(C9=C(C)SC([C@H](CC(N)=O)N1)=N9)=O)=N7)=O)=O)[C@H](C)C%10CO%10)=N5)=N4)N=C(C%11=NC(C(NC(C(NC(C(N[C@@H](C)C(O)=O)=O)=C)=O)=C)=O)=CS%11)C=C3)=N2 |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Thermobispora bispora DSM 43833 NCBITaxon:469371 |
SOURCE_ASSERTION | mibig:BGC0001860 | PMID:26675417 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001860 | Thermobispora bispora DSM 43833 NCBITaxon:469371 |
CLUSTER_DEMONSTRATED | genbank:CP001874.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001860 | MIBIG | 4 |
This page is generated from data/natural_products/amino_acids_and_peptides/thiomuracin.yaml, which is generated from the committed inventories. Neither is edited by hand.