NaturalProductMech

thioviridamide

naturalproductmech:mibig-349eb3ff75 MINTED SEEDED

Structure

Standard InChIKeyTZZVQGHYMBASEV-VZCXRCSSSA-O
SMILESCCC(C)C1NC(=O)C(CS\C=C/NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(C)NC1=O)C(O)C1=CN(C)C=[N+]1C)NC(=O)C(C)NC(=S)C(C)NC(=S)C(C)NC(=S)C(C)NC(=S)C(CCSC)NC(=S)C(NC(=O)C(C)(O)CC(C)=O)C(C)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA011569

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces olivoviridis
NCBITaxon:67338
SOURCE_ASSERTION mibig:BGC0000625 PMID:23995943

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces atroolivaceus
NCBITaxon:66869
LOTUS DOI:10.1038/JA.2006.1
Streptomyces atroolivaceus
NCBITaxon:66869
LOTUS DOI:10.1038/JA.2006.2
Streptomyces atroolivaceus
NCBITaxon:66869
LOTUS DOI:10.1128/AEM.01978-13
Streptomyces olivoviridis
NCBITaxon:67338
LOTUS DOI:10.1038/JA.2006.1
Streptomyces olivoviridis
NCBITaxon:67338
LOTUS DOI:10.1038/JA.2006.2
Streptomyces olivoviridis
NCBITaxon:67338
LOTUS DOI:10.1128/AEM.01978-13

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000625 Streptomyces olivoviridis
NCBITaxon:67338
CLUSTER_UNSTATED genbank:AB819757.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000625MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/thioviridamide.yaml, which is generated from the committed inventories. Neither is edited by hand.