trunkamide

naturalproductmech:mibig-39d1c4dde2 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKey	UTERRJKSLJLXTA-LVPVHDLMSA-N
SMILES	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C3=N[C@@H](CS3)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)COC(C)(C)C=C)[C@@H](C)OC(C)(C)C=C)CC4=CC=CC=C4)C
Stereochemistry	fully defined
Cross-references	pubchem:9811230

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
uncultured Prochloron sp. NCBITaxon:259942	SOURCE_ASSERTION	mibig:BGC0000478	PMID:18425112
uncultured Prochloron sp. NCBITaxon:259942	SOURCE_ASSERTION	mibig:BGC0000482	DOI:10.1021/jo026464s

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Lissoclinum NCBITaxon:13109	LOTUS	DOI:10.1071/CH9960659

Biosynthetic gene clusters 2

Accession	Host	Locus evidence	Genome
mibig:BGC0000478	uncultured Prochloron sp. NCBITaxon:259942	CLUSTER_DEMONSTRATED	genbank:EU290743.1
mibig:BGC0000482	uncultured Prochloron sp. NCBITaxon:259942	CLUSTER_UNSTATED	genbank:EU290744.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Explore across X-Mech

AntibioticMech (trunkamide) ↗ MediaIngredientMech (naturalproductmech:mibig-39d1c4dde2) ↗ TaxonMech: uncultured Prochloron sp. (NCBITaxon:259942) ↗ TaxonMech: uncultured Prochloron sp. (NCBITaxon:259942) ↗ PathwayMech (mibig:BGC0000478) ↗ PathwayMech (mibig:BGC0000482) ↗

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000478, BGC0000482. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source concept	Source	Version
BGC0000478	MIBIG	4
BGC0000482	MIBIG	4

This page is generated from data/natural_products/amino_acids_and_peptides/trunkamide.yaml, which is generated from the committed inventories. Neither is edited by hand.