tubulysin I
naturalproductmech:mibig-87460012be MINTED SEEDED
Structure
| Standard InChIKey | ADNHOQYEDVQAGD-XYFJCUIBSA-N |
|---|---|
| SMILES | [H][C@](C)(CC)[C@]([H])(NC(=O)[C@H]1CCCCN1C)C(=O)N(COC(C)=O)[C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@H](C[C@H](C)C(O)=O)CC1=CC=C(O)C=C1)C(C)C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA011260, pubchem:11422937 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Cystobacter sp. SBCb004 NCBITaxon:764904 |
SOURCE_ASSERTION | mibig:BGC0001344 | PMID:20338521 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Archangium gephyra NCBITaxon:48 |
LOTUS | DOI:10.1002/ANIE.200460147 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001344 | Cystobacter sp. SBCb004 NCBITaxon:764904 |
CLUSTER_UNSTATED | genbank:GU002154.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001344 | MIBIG | 4 |
This page is generated from data/natural_products/amino_acids_and_peptides/tubulysin-i.yaml, which is generated from the committed inventories. Neither is edited by hand.