vanchrobactin
CHEBI:157682 EXACT SEEDED
A catechol-type natural product that is composed of 2,3-dihydroxybenzoic acid, D-arginine and L-serine joined in sequence by peptide linkages. It is a siderophore synthesized by the bacterial fish pathogen Vibrio anguillarum.
Structure
| Standard InChIKey | LXNCWECCTQQXPQ-ZJUUUORDSA-N |
|---|---|
| SMILES | NC(=N)NCCC[C@@H](NC(=O)C1=CC=CC(O)=C1O)C(=O)N[C@@H](CO)C(O)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA016075, pubchem:16658367 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Vibrio anguillarum RV22 NCBITaxon:989499 |
SOURCE_ASSERTION | mibig:BGC0000454 | PMID:17159203 |
| Vibrio campbellii NCBITaxon:680 |
SOURCE_ASSERTION | mibig:BGC0002415 | PMID:22275102 |
Occurrences 5
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Vibrio campbellii NCBITaxon:1088888 |
CHEBI | PMID:20521785 |
| Vibrio anguillarum NCBITaxon:55601 |
LOTUS | DOI:10.1016/J.TETLET.2006.07.104 |
| Vibrio anguillarum NCBITaxon:55601 |
LOTUS | DOI:10.1099/MIC.0.29298-0 |
| Vibrio anguillarum NCBITaxon:55601 |
CHEBI | PMID:23765994 |
| Vibrio NCBITaxon:662 |
LOTUS | DOI:10.1021/NP900750G |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000454 | Vibrio anguillarum RV22 NCBITaxon:989499 |
CLUSTER_UNSTATED | genbank:AM168450.2 |
| mibig:BGC0002415 | Vibrio campbellii NCBITaxon:680 |
CLUSTER_UNSTATED | genbank:CP030789.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000454, BGC0002415. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000454 | MIBIG | 5 |
| BGC0002415 | MIBIG | 2 |
| CHEBI:157682 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/vanchrobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.