NaturalProductMech

Browse · Amino acids and peptides · vibrioferrin

vibrioferrin

naturalproductmech:mibig-c1b0b2a6f8 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyFPHRKFJYHKRDFJ-LWYCVJHGSA-N
SMILESC[C@@H](C(=O)NCCC(C(=O)O)C(CC(=O)O)(C(=O)O)O)N1C(=O)CC[C@]1(C(=O)O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:197680

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Vibrio alginolyticus
Strain: MVPO1
NCBITaxon:663		 SOURCE_ASSERTION mibig:BGC0000947
PMID:17593352, https://www.ncbi.nlm.nih.gov/nuccore/DQ201184.2
  • reference
    PMID:17593352
    evidence type
    DATABASE_ASSERTION
    notes
    MIBiG BGC0000947 entry version 5; citation taken from the entry level
  • reference
    https://www.ncbi.nlm.nih.gov/nuccore/DQ201184.2
    evidence type
    CURATOR_INFERENCE
    notes
    Strain context: MVPO1. DQ201184.2 spells the strain MVPO1 (letter O); the PMID:17593352 publisher abstract at DOI:10.1007/s00203-007-0261-6 spells it MVP01 (zero). Preserve the deposited literal and the unresolved spelling discrepancy, not a silent normalization or a claim of two different strains. This qualifies the source locus only; exact product identity remains unresolved in #929. No evidence grade changes. See issue #933. Taxon identity and evidence grade are unchanged; this is not a species-wide experiment. MIBiG source row BGC0000947:1; SHA256 c1452d9f35f0197165f3205d6bb9cfa300df22c601e3f524c6df8dbf48bedd3a. Curator: codex; date: 2026-10-13.

Occurrences 7

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1021/IC9016883
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1093/OXFORDJOURNALS.JBCHEM.A124432
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1111/J.1574-6968.2011.02389.X
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1128/JB.00162-13
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1128/JB.185.23.6938-6949.2003
Vibrio parahaemolyticus
NCBITaxon:670		 LOTUS DOI:10.1271/BBB.110379
Vibrio alginolyticus
NCBITaxon:663		 LOTUS DOI:10.1007/S00203-007-0261-6

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000947 Vibrio alginolyticus
NCBITaxon:663 		CLUSTER_UNSTATED genbank:DQ201184.2

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (0 causal) 7 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT vibrioferrin naturalproductmech:mibig-c1b0b2a6f8 Amino acids and peptides TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

Explore across X-Mech

AntibioticMech (vibrioferrin) ↗ MediaIngredientMech (naturalproductmech:mibig-c1b0b2a6f8) ↗ TaxonMech: Vibrio alginolyticus (NCBITaxon:663) ↗ PathwayMech (mibig:BGC0000947) ↗

Open questions 1

curator-vibrioferrin-constitution — Does the imported BGC0000947 constitution identify the experimentally established vibrioferrin product?

Provenance

Source conceptSourceVersion
BGC0000947MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/vibrioferrin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.