NaturalProductMech

vibrioferrin

CHEBI:84585 EXACT SEEDED

A tricarboxylic acid that is citric acid in which the pro-R carboxy group has been esterified with the primary hydroxy group of 2-hydroxy-1-{(2S)-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}-5-oxoproline. It is a siderophore isolated from bacteria closely associated or symbiotic with toxic, bloom-forming dinoflagellates.

Structure

Standard InChIKeyIGQXNKDXMPSELX-BIAKFKOBSA-N
SMILESO=C1CCC(O)(C(O)=O)N1[C@@H](C)C(NCCOC(C[C@](C(O)=O)(O)CC(O)=O)=O)=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:197680, npatlas:NPA024673

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Vibrio parahaemolyticus
NCBITaxon:670
SOURCE_ASSERTION mibig:BGC0000946 PMID:14617658
Azotobacter vinelandii CA
NCBITaxon:1283330
SOURCE_ASSERTION mibig:BGC0002527 DOI:10.1021/ic9016883

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Azotobacter vinelandii
NCBITaxon:354
LOTUS DOI:10.1128/AEM.03160-15
Vibrio alginolyticus
NCBITaxon:663
CHEBI PMID:22146715
Vibrio parahaemolyticus
NCBITaxon:670
CHEBI DOI: 10.1111/j.1574-6968.1992.tb05311.x
Vibrio parahaemolyticus
NCBITaxon:670
LOTUS DOI:10.1093/OXFORDJOURNALS.JBCHEM.A124432
Vibrio parahaemolyticus
NCBITaxon:670
LOTUS DOI:10.1128/JB.185.23.6938-6949.2003

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000946 Vibrio parahaemolyticus
NCBITaxon:670
CLUSTER_UNSTATED genbank:AB082123.1
mibig:BGC0002527 Azotobacter vinelandii CA
NCBITaxon:1283330
CLUSTER_UNSTATED genbank:CP005094.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000946, BGC0002527. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000946MIBIG5
BGC0002527MIBIG2
CHEBI:84585CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/vibrioferrin.yaml, which is generated from the committed inventories. Neither is edited by hand.