NaturalProductMech

zelkovamycin D

naturalproductmech:mibig-542b01f1fe MINTED SEEDED

Structure

Standard InChIKeyIDQDOHKLXZSZIG-VQJCRCMASA-N
SMILESCC[C@H]1NC(=O)CNC(=O)[C@](C)(C(C)=O)NC(=O)[C@H](CC2=CNC3=C2C(OC)=CC=C3)NC(=O)C2=CSC(=N2)[C@@H](C)NC(=O)CN(C)C(=O)/C(=C/CO)NC1=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA032261

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Actinomadura graeca
NCBITaxon:2750812
BGC_CORRELATED mibig:BGC0002370 PMID:33216552

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Kitasatospora
NCBITaxon:2063
LOTUS DOI:10.1021/ACS.ORGLETT.0C03565

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002370 Actinomadura graeca
NCBITaxon:2750812
CLUSTER_CORRELATED genbank:CP059572.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002370MIBIG2

This page is generated from data/natural_products/amino_acids_and_peptides/zelkovamycin-d.yaml, which is generated from the committed inventories. Neither is edited by hand.