zorbamycin
CHEBI:67811 EXACT SEEDED antimicrobial unspecified
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A glycopeptide antibiotic found in Streptomyces flavoviridis.
Structure
| Standard InChIKey | UJKRUPHWCPAJIL-CPLCKGKLSA-N |
|---|---|
| SMILES | [H][C@](N)(CN[C@@]([H])(CC(N)=O)C1=NC(N)=C(C)C(=N1)C(=O)N[C@]([H])(C(=O)N[C@]([H])(CCO)[C@@]([H])(O)[C@]([H])(C)C(=O)N[C@]([H])(C(=O)NCCC1=N[C@]([H])(CS1)C1=NC(=CS1)C(=O)NCCC(N)=N)C(C)(C)O)[C@@]([H])(O[C@@H]1O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)C1=CNC=N1)C(N)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA08777, pubchem:70697970 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces flavoviridis NCBITaxon:28893 |
BGC_CHARACTERIZED | mibig:BGC0001058 | PMID:17311457 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces flavoviridis NCBITaxon:28893 |
LOTUS | DOI:10.1021/NP060592K |
| Streptomyces flavoviridis NCBITaxon:28893 |
LOTUS | DOI:10.1021/NP060592K.S001 |
| Streptomyces flavoviridis NCBITaxon:28893 |
CHEBI | PMID:21210656 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001058 | Streptomyces flavoviridis NCBITaxon:28893 |
CLUSTER_DEMONSTRATED | genbank:EU670723.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — CHEBI:67811 (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001058 | MIBIG | 5 |
| CHEBI:67811 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/zorbamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.