NaturalProductMech

zorbamycin

CHEBI:67811 EXACT SEEDED antimicrobial unspecified

A glycopeptide antibiotic found in Streptomyces flavoviridis.

Structure

Standard InChIKeyUJKRUPHWCPAJIL-CPLCKGKLSA-N
SMILES[H][C@](N)(CN[C@@]([H])(CC(N)=O)C1=NC(N)=C(C)C(=N1)C(=O)N[C@]([H])(C(=O)N[C@]([H])(CCO)[C@@]([H])(O)[C@]([H])(C)C(=O)N[C@]([H])(C(=O)NCCC1=N[C@]([H])(CS1)C1=NC(=CS1)C(=O)NCCC(N)=N)C(C)(C)O)[C@@]([H])(O[C@@H]1O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)C1=CNC=N1)C(N)=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA08777, pubchem:70697970

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, saccharide, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces flavoviridis
NCBITaxon:28893
BGC_CHARACTERIZED mibig:BGC0001058 PMID:17311457

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces flavoviridis
NCBITaxon:28893
LOTUS DOI:10.1021/NP060592K
Streptomyces flavoviridis
NCBITaxon:28893
LOTUS DOI:10.1021/NP060592K.S001
Streptomyces flavoviridis
NCBITaxon:28893
CHEBI PMID:21210656

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001058 Streptomyces flavoviridis
NCBITaxon:28893
CLUSTER_DEMONSTRATED genbank:EU670723.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0001058MIBIG5
CHEBI:67811CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/zorbamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.