NaturalProductMech

2'-chloropentostatin

naturalproductmech:mibig-e015ff9a38 MINTED SEEDED

Structure

Standard InChIKeyBIJKEIIWFILUFX-COBSUARPSA-N
SMILESC1[C@H](C2=C(NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)Cl)O/C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)N
Stereochemistryfully defined

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Actinomadura sp. ATCC 39365
NCBITaxon:1676613
SOURCE_ASSERTION mibig:BGC0001484 DOI:10.7164/antibiotics.38.1008

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Actinomadura
NCBITaxon:1988
LOTUS DOI:10.1128/AEM.00078-17

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001484 Actinomadura sp. ATCC 39365
NCBITaxon:1676613
CLUSTER_UNSTATED genbank:KP025768.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001484MIBIG3

This page is generated from data/natural_products/carbohydrates/2-chloropentostatin.yaml, which is generated from the committed inventories. Neither is edited by hand.