aristeromycin
naturalproductmech:mibig-8918d2a0ba MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | UGRNVLGKAGREKS-GCXDCGAKSA-N |
|---|---|
| SMILES | C1[C@@H]([C@H]([C@H]([C@@H]1N2C=NC3=C2N=CN=C3N)O)O)CO |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA018381, pubchem:65269 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora haikouensis NCBITaxon:686309 |
BGC_CHARACTERIZED | mibig:BGC0002435 | PMID:30217843 |
| Streptomyces citricolor NCBITaxon:212427 |
SOURCE_ASSERTION | mibig:BGC0001514 | PMID:27577857 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Saccharothrix NCBITaxon:2071 |
LOTUS | DOI:10.1016/S0031-9422(00)95163-X |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.1016/0040-4039(94)88354-8 |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.1016/S0040-4039(00)60621-4 |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.1021/JA00308A047 |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.1039/P19940003533 |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.1248/CPB.20.940 |
| Streptomyces citricolor NCBITaxon:212427 |
LOTUS | DOI:10.7164/ANTIBIOTICS.21.255 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002435 | Micromonospora haikouensis NCBITaxon:686309 |
CLUSTER_DEMONSTRATED | genbank:FMCW01000024.1 |
| mibig:BGC0001514 | Streptomyces citricolor NCBITaxon:212427 |
CLUSTER_UNSTATED | genbank:LC054541.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001514, BGC0002435. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002435 | MIBIG | 3 |
| BGC0001514 | MIBIG | 5 |
This page is generated from data/natural_products/carbohydrates/aristeromycin.yaml, which is generated from the committed inventories. Neither is edited by hand.