butirosin A
CHEBI:65112 EXACT SEEDED antimicrobial unspecified
A butirosin that consists of neamine in which is substituted at position 2 by a β-D-xylofuranosyl and at position 4 by an (S)-2-hydroxy-4-aminobutyryl group.
Structure
| Standard InChIKey | XEQLFNPSYWZPOW-SVRMBHBBSA-N |
|---|---|
| SMILES | C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O)O[C@H]2[C@@H]([C@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N |
| Stereochemistry | fully defined |
| Cross-references | pubchem:12302171 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Bacillus circulans NCBITaxon:1397 |
SOURCE_ASSERTION | mibig:BGC0000693 | PMID:11132962 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Bacillus circulans NCBITaxon:1397 |
LOTUS | DOI:10.7164/ANTIBIOTICS.39.1346 |
| Bacillus circulans NCBITaxon:1397 |
LOTUS | DOI:10.7164/ANTIBIOTICS.53.1158 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000693 | Bacillus circulans NCBITaxon:1397 |
CLUSTER_UNSTATED | genbank:AB097196.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:65112 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000693 | MIBIG | 5 |
| CHEBI:65112 | CHEBI | 3-star |
This page is generated from data/natural_products/carbohydrates/butirosin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.