butirosin B
CHEBI:65110 EXACT SEEDED antimicrobial unspecified
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A butirosin that consists of neamine in which is substituted at position 2 by a β-D-ribofuranosyl and at position 4 by an (S)-2-hydroxy-4-aminobutyryl group.
Structure
| Standard InChIKey | XEQLFNPSYWZPOW-HBYCGHPUSA-N |
|---|---|
| SMILES | C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O)O[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N |
| Stereochemistry | fully defined |
| Cross-references | pubchem:12302172 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Bacillus circulans NCBITaxon:1397 |
SOURCE_ASSERTION | mibig:BGC0000693 | PMID:11132962 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000693 | Bacillus circulans NCBITaxon:1397 |
CLUSTER_UNSTATED | genbank:AB097196.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — CHEBI:65110 (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000693 | MIBIG | 5 |
| CHEBI:65110 | CHEBI | 3-star |
This page is generated from data/natural_products/carbohydrates/butirosin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.