gentamicin
naturalproductmech:mibig-ac32edbacd MINTED SEEDED
Structure
| Standard InChIKey | BDTQHFBWYNCGHN-CUYCKOLISA-N |
|---|---|
| SMILES | CN[C@H]1[C@@H](O)CO[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA09026, pubchem:72396 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora echinospora NCBITaxon:1877 |
SOURCE_ASSERTION | mibig:BGC0000696 | PMID:15376556 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Micromonospora NCBITaxon:1873 |
LOTUS | DOI:10.1021/JM00340A034 |
| Micromonospora echinospora NCBITaxon:1877 |
LOTUS | DOI:10.7164/ANTIBIOTICS.57.436 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000696 | Micromonospora echinospora NCBITaxon:1877 |
CLUSTER_UNSTATED | genbank:AJ628149.4 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database | ACTIVE | pubchem.aid:1195 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000696 | MIBIG | 5 |
This page is generated from data/natural_products/carbohydrates/gentamicin.yaml, which is generated from the committed inventories. Neither is edited by hand.