NaturalProductMech

oxetanocin A

CHEBI:86012 EXACT SEEDED antibacterial

A nucleoside analogue found in Bacillus megaterium in which an adenine moiety is attached to position 2 of a of an oxetane ring which is substituted at positions 3 and 4 by hydroxymethyl groups.

Structure

Standard InChIKeyLMJVXGOFWKVXAW-OXOINMOOSA-N
SMILESC1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@H](O3)CO)CO
Stereochemistryfully defined

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Bacillus megaterium
NCBITaxon:1404
SOURCE_ASSERTION mibig:BGC0001725 DOI:10.7164/antibiotics.39.1623

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Bacillus megaterium
NCBITaxon:1404
LOTUS DOI:10.7164/ANTIBIOTICS.39.1626
Bacillus megaterium
NCBITaxon:1404
CHEBI PMID:3025147

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001725 Bacillus megaterium
NCBITaxon:1404
CLUSTER_UNSTATED genbank:AB005787.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0001725MIBIG3
CHEBI:86012CHEBI3-star

This page is generated from data/natural_products/carbohydrates/oxetanocin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.