paromomycin
naturalproductmech:mibig-fb83d937b9 MINTED SEEDED
Structure
| Standard InChIKey | UOZODPSAJZTQNH-VZXHOKRSSA-N |
|---|---|
| SMILES | NC[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA0635, pubchem:165580 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces rimosus subsp. paromomycinus NCBITaxon:92743 |
SOURCE_ASSERTION | mibig:BGC0000712 | PMID:19362651 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces fradiae NCBITaxon:1906 |
LOTUS | DOI:10.1039/B808734B |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000712 | Streptomyces rimosus subsp. paromomycinus NCBITaxon:92743 |
CLUSTER_UNSTATED | genbank:AJ628955.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database | ACTIVE | pubchem.aid:1195 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000712 | MIBIG | 5 |
This page is generated from data/natural_products/carbohydrates/paromomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.