paulomycin
naturalproductmech:mibig-d496b2b225 MINTED SEEDED
Structure
| Standard InChIKey | HYYDZRXDSYTIEH-MQTRCCAJSA-N |
|---|---|
| SMILES | C/C=C(/C(=O)O[C@@H]1[C@H](OC([C@@H]([C@@H]1O[C@@H]2C[C@H]([C@H]([C@H](O2)C)O)OC)O)C3(CC(=O)C(=C(C3=O)C(=O)O)N)O)COC(=O)C)\N=C=S |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6450320 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces paulus NCBITaxon:285551 |
SOURCE_ASSERTION | mibig:BGC0001731 | PMID:27001601 |
| Streptomyces sp. YN86 NCBITaxon:1484062 |
SOURCE_ASSERTION | mibig:BGC0001732 | PMID:25822496 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0120542 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-019-10329-9 |
| Streptomyces paulus NCBITaxon:285551 |
LOTUS | DOI:10.1007/S00253-019-10329-9 |
| Streptomyces paulus NCBITaxon:285551 |
LOTUS | DOI:10.1186/S12934-016-0452-4 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001731 | Streptomyces paulus NCBITaxon:285551 |
CLUSTER_UNSTATED | genbank:KJ721164.1 |
| mibig:BGC0001732 | Streptomyces sp. YN86 NCBITaxon:1484062 |
CLUSTER_UNSTATED | genbank:KJ721165.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001731, BGC0001732. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001731 | MIBIG | 5 |
| BGC0001732 | MIBIG | 5 |
This page is generated from data/natural_products/carbohydrates/paulomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.