NaturalProductMech

pyralomicin 1a

naturalproductmech:mibig-d8142cfdc3 MINTED SEEDED

Structure

Standard InChIKeyJPPZZIRKTBZEAJ-JLBIYAHBSA-N
SMILESCO[C@H]1[C@H](O)[C@@H](O)[C@@H](C=C1CO)N1C(Cl)=CC2=C1OC1=C(C(O)=C(Cl)C=C1C)C2=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA013382, pubchem:3072006

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Nonomuraea spiralis
NCBITaxon:46182
SOURCE_ASSERTION mibig:BGC0001038 PMID:23607523

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Nonomuraea spiralis
NCBITaxon:46182
LOTUS DOI:10.1021/NP400159A
Nonomuraea spiralis
NCBITaxon:46182
LOTUS DOI:10.7164/ANTIBIOTICS.48.435
Nonomuraea spiralis
NCBITaxon:46182
LOTUS DOI:10.7164/ANTIBIOTICS.49.651

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001038 Nonomuraea spiralis
NCBITaxon:46182
CLUSTER_DEMONSTRATED genbank:JX424761.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001038MIBIG5

This page is generated from data/natural_products/carbohydrates/pyralomicin-1a.yaml, which is generated from the committed inventories. Neither is edited by hand.