NaturalProductMech

streptothricin D

CHEBI:60828 EXACT SEEDED antimicrobial unspecified

A streptothricin in which the peptide side-chain consists of 3 units of β-lysine.

Structure

Standard InChIKeyWUJTXMVGXDQPNN-OTQKCRDJSA-N
SMILESNCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)N[C@@H]1[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]1\N=C1\N[C@H]2[C@H](N1)C(=O)NC[C@H]2O
Stereochemistryfully defined

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces rochei NBRC 12908
NCBITaxon:1928
SOURCE_ASSERTION mibig:BGC0000432 DOI:10.1038/nchembio.1040

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1007/BF02976852
Streptomyces qinlingensis
NCBITaxon:360709
LOTUS DOI:10.1007/S00253-018-8748-4
Streptomyces qinlingensis
NCBITaxon:360709
LOTUS DOI:10.1007/S11427-013-4504-2
Streptomyces qinlingensis
NCBITaxon:360709
LOTUS DOI:10.1038/JA.2007.96
Streptomyces nojiriensis
NCBITaxon:66374
LOTUS DOI:10.7164/ANTIBIOTICS.40.1140

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000432 Streptomyces rochei NBRC 12908
NCBITaxon:1928
CLUSTER_DEMONSTRATED genbank:AB684619.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0000432MIBIG6
CHEBI:60828CHEBI3-star

This page is generated from data/natural_products/carbohydrates/streptothricin-d.yaml, which is generated from the committed inventories. Neither is edited by hand.