streptozotocin
naturalproductmech:mibig-34dab48dce MINTED SEEDED
Structure
| Standard InChIKey | ZSJLQEPLLKMAKR-YDEIVXIUSA-N |
|---|---|
| SMILES | CN(N=O)C(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA032744 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces achromogenes subsp. streptozoticus NCBITaxon:285532 |
BGC_CHARACTERIZED | mibig:BGC0002313 | PMID:30728519 |
| Streptomyces achromogenes subsp. streptozoticus NCBITaxon:285532 |
SOURCE_ASSERTION | mibig:BGC0002294 | DOI:10.3390/ijms13055751 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces achromogenes NCBITaxon:67255 |
LOTUS | DOI:10.1021/JA00994A053 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002313 | Streptomyces achromogenes subsp. streptozoticus NCBITaxon:285532 |
CLUSTER_DEMONSTRATED | genbank:MK303572.1 |
| mibig:BGC0002294 | Streptomyces achromogenes subsp. streptozoticus NCBITaxon:285532 |
CLUSTER_DEMONSTRATED | genbank:MK440296.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0002294, BGC0002313. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002313 | MIBIG | 3 |
| BGC0002294 | MIBIG | 3 |
This page is generated from data/natural_products/carbohydrates/streptozotocin.yaml, which is generated from the committed inventories. Neither is edited by hand.