tunicamycin B1
CHEBI:64248 EXACT SEEDED antimicrobial unspecified
A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety.
Structure
| Standard InChIKey | QYVMTFXNKNWWFX-YGTZKZKGSA-N |
|---|---|
| SMILES | CCCCCCCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:56927834 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces chartreusis NRRL 3882 NCBITaxon:1079985 |
BGC_CHARACTERIZED | mibig:BGC0000880 | PMID:22717438 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000880 | Streptomyces chartreusis NRRL 3882 NCBITaxon:1079985 |
CLUSTER_DEMONSTRATED | genbank:HQ172897.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:64248 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000880 | MIBIG | 4 |
| CHEBI:64248 | CHEBI | 3-star |
This page is generated from data/natural_products/carbohydrates/tunicamycin-b1.yaml, which is generated from the committed inventories. Neither is edited by hand.