γ-butyrolactone
CHEBI:42639 EXACT SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.
Structure
| Standard InChIKey | YEJRWHAVMIAJKC-UHFFFAOYSA-N |
|---|---|
| SMILES | C1CC(=O)OC1 |
| Stereochemistry | fully defined |
Filing pathway
Fatty acids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces acidiscabies NCBITaxon:42234 |
SOURCE_ASSERTION | mibig:BGC0000850 | PMID:19465647 |
Occurrences 18
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Coffea arabica NCBITaxon:13443 |
LOTUS | DOI:10.1021/JF60160A010 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1007/S13213-010-0034-3 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-008-1802-X |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1021/ACSSYNBIO.7B00425 |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1007/S00253-008-1802-X |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1021/ACSSYNBIO.7B00425 |
| Streptomyces hygroscopicus NCBITaxon:1912 |
LOTUS | DOI:10.1002/BIT.24965 |
| Mangifera indica NCBITaxon:29780 |
LOTUS | DOI:10.1021/JF00097A028 |
| Streptomyces avermitilis NCBITaxon:33903 |
LOTUS | DOI:10.1007/BF02932133 |
| Gossypium hirsutum NCBITaxon:3635 |
LOTUS | DOI:10.1021/JF60200A011 |
| Citrullus lanatus NCBITaxon:3654 |
LOTUS | DOI:10.1271/BBB1961.49.3145 |
| Streptomyces nodosus NCBITaxon:40318 |
LOTUS | DOI:10.1007/S00253-015-7060-9 |
| Capsicum annuum NCBITaxon:4072 |
LOTUS | DOI:10.1006/JFCA.1997.0535 |
| Aesculus hippocastanum NCBITaxon:43364 |
LOTUS | DOI:10.1080/10412905.1994.9698335 |
| Glycyrrhiza glabra NCBITaxon:49827 |
LOTUS | DOI:10.1021/JF60214A042 |
| Streptomyces ghanaensis NCBITaxon:67581 |
LOTUS | DOI:10.1007/S12223-018-0614-3 |
| Aethus indicus NCBITaxon:696237 |
LOTUS | DOI:10.1515/ZNC-1984-3-422 |
| Streptomyces acidiscabies NCBITaxon:42234 |
LOTUS | DOI:10.1128/JB.00437-09 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000850 | Streptomyces acidiscabies NCBITaxon:42234 |
CLUSTER_UNSTATED | genbank:FJ821515.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000850 | MIBIG | 5 |
| CHEBI:42639 | CHEBI | 3-star |
This page is generated from data/natural_products/fatty_acids/butyrolactone.yaml, which is generated from the committed inventories. Neither is edited by hand.