NaturalProductMech

γ-butyrolactone

CHEBI:42639 EXACT SEEDED

A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.

Structure

Standard InChIKeyYEJRWHAVMIAJKC-UHFFFAOYSA-N
SMILESC1CC(=O)OC1
Stereochemistryfully defined

Filing pathway

Fatty acids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces acidiscabies
NCBITaxon:42234
SOURCE_ASSERTION mibig:BGC0000850 PMID:19465647

Occurrences 18

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Coffea arabica
NCBITaxon:13443
LOTUS DOI:10.1021/JF60160A010
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1007/S13213-010-0034-3
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S00253-008-1802-X
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1021/ACSSYNBIO.7B00425
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S00253-008-1802-X
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1021/ACSSYNBIO.7B00425
Streptomyces hygroscopicus
NCBITaxon:1912
LOTUS DOI:10.1002/BIT.24965
Mangifera indica
NCBITaxon:29780
LOTUS DOI:10.1021/JF00097A028
Streptomyces avermitilis
NCBITaxon:33903
LOTUS DOI:10.1007/BF02932133
Gossypium hirsutum
NCBITaxon:3635
LOTUS DOI:10.1021/JF60200A011
Citrullus lanatus
NCBITaxon:3654
LOTUS DOI:10.1271/BBB1961.49.3145
Streptomyces nodosus
NCBITaxon:40318
LOTUS DOI:10.1007/S00253-015-7060-9
Capsicum annuum
NCBITaxon:4072
LOTUS DOI:10.1006/JFCA.1997.0535
Aesculus hippocastanum
NCBITaxon:43364
LOTUS DOI:10.1080/10412905.1994.9698335
Glycyrrhiza glabra
NCBITaxon:49827
LOTUS DOI:10.1021/JF60214A042
Streptomyces ghanaensis
NCBITaxon:67581
LOTUS DOI:10.1007/S12223-018-0614-3
Aethus indicus
NCBITaxon:696237
LOTUS DOI:10.1515/ZNC-1984-3-422
Streptomyces acidiscabies
NCBITaxon:42234
LOTUS DOI:10.1128/JB.00437-09

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000850 Streptomyces acidiscabies
NCBITaxon:42234
CLUSTER_UNSTATED genbank:FJ821515.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000850MIBIG5
CHEBI:42639CHEBI3-star

This page is generated from data/natural_products/fatty_acids/butyrolactone.yaml, which is generated from the committed inventories. Neither is edited by hand.