NaturalProductMech

lipopolysaccharide

naturalproductmech:mibig-ad23b710ca MINTED SEEDED

Structure

Standard InChIKeyYPXVSQSYDIMPDZ-AUUHBOKRSA-N
SMILESCCCCCCCCCCCCCCCC1[C@H](OC([C@H]([C@@H]1OC(=O)CC(CCCCCCCCCCC)O)O)CO[C@H]2[C@H](C([C@@H](C(O2)CO[C@@]3(CC([C@H](C(O3)C(CO)O)O[C@H]4[C@@H](C([C@@H](C(O4)C(CO)O)OP(=O)(O)OP(=O)(O)OCCN)O[C@@H]5[C@@H](C([C@@H](C(O5)C(CO[C@@H]6[C@@H](C([C@](CO6)(C(CO)O)O)O)O)O)OP(=O)(O)O)O[C@@H]7C(C([C@@H](C(O7)CO[C@@H]8C(C([C@H](C(O8)CO)O)O)O)O)O[C@@H]9C(C([C@H](C(O9)CO)O)O)O[C@@H]1C(C([C@@H](C(O1)CO)O[C@@H]1C(C([C@H](C(O1)CO)O)OC1[C@@H](C(C([C@@H](O1)C)O[C@@H]1C(C([C@@H](C(O1)CO)O)O[C@@H]1C(C[C@H](C(O1)C)O)O)O[C@@H]1C(C([C@H](C(O1)CO)O)O)O)O)O)O)O)O[C@@H]1[C@H](C([C@@H](C(O1)CO)O)O)NC(=O)C)O)O)O)O[C@@]1(CC([C@H](C(O1)C(CO)O)O)O[C@@]1(CC([C@H](C(O1)C(CO)O)O)O)C(=O)O)C(=O)O)C(=O)O)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)CP(=O)(O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:11970143

Filing pathway

Fatty acids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.

Producer organisms 5

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Brucella melitensis
NCBITaxon:29459
SOURCE_ASSERTION mibig:BGC0000772 PMID:9784561
Escherichia coli
NCBITaxon:562
SOURCE_ASSERTION mibig:BGC0000773 PMID:7677991
Legionella pneumophila
NCBITaxon:446
SOURCE_ASSERTION mibig:BGC0000775 PMID:11043980
Escherichia coli
NCBITaxon:562
SOURCE_ASSERTION mibig:BGC0000776 PMID:12374825
Escherichia coli
NCBITaxon:562
SOURCE_ASSERTION mibig:BGC0000777 PMID:12374825

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Brucella melitensis
NCBITaxon:29459
LOTUS DOI:10.1128/IAI.66.11.5485-5493.1998
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1128/JB.175.1.148-158.1993
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1128/JB.184.21.5912-5925.2002

Biosynthetic gene clusters 5

AccessionHostLocus evidenceGenome
mibig:BGC0000772 Brucella melitensis
NCBITaxon:29459
CLUSTER_UNSTATED genbank:AF047478.1
mibig:BGC0000773 Escherichia coli
NCBITaxon:562
CLUSTER_UNSTATED genbank:AF125322.1
mibig:BGC0000775 Legionella pneumophila
NCBITaxon:446
CLUSTER_UNSTATED genbank:AJ007311.1
mibig:BGC0000776 Escherichia coli
NCBITaxon:562
CLUSTER_UNSTATED genbank:AJ426044.2
mibig:BGC0000777 Escherichia coli
NCBITaxon:562
CLUSTER_UNSTATED genbank:AJ426045.2

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000772, BGC0000773, BGC0000775, BGC0000776, BGC0000777. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000772MIBIG5
BGC0000773MIBIG3
BGC0000775MIBIG3
BGC0000776MIBIG3
BGC0000777MIBIG3

This page is generated from data/natural_products/fatty_acids/lipopolysaccharide.yaml, which is generated from the committed inventories. Neither is edited by hand.