1233A
naturalproductmech:mibig-929bdafcd6 MINTED SEEDED
Structure
| Standard InChIKey | ODCZJZWSXPVLAW-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(=CC(=O)O)C=C(C)CC(C)CCCCC1OC(=O)C1CO |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6440895, npatlas:NPA032750 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fusarium sp. NCBITaxon:29916 |
BGC_CHARACTERIZED | mibig:BGC0002525 | PMID:32139880 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002525 | Fusarium sp. NCBITaxon:29916 |
CLUSTER_DEMONSTRATED | genbank:LC516401.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 2
| Assay | Result | Reference |
|---|---|---|
| Rat hydroxymethylglutaryl-CoA synthase 1 (Lanosterol biosynthesis pathway) | ACTIVE | PMID:2890166 |
| Rat hydroxymethylglutaryl-CoA synthase 1 (Lanosterol biosynthesis pathway) | ACTIVE | PMID:8094614 |
Open questions 1
needs-a-name — This record is labelled '1233A', which is a label from the cited paper's own numbering rather than a compound name. Resolve a name from the literature or a structure registry.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002525 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/1233a.yaml, which is generated from the committed inventories. Neither is edited by hand.