NaturalProductMech

4-epi-15-epi-brefeldin A

naturalproductmech:mibig-302fcb080c MINTED SEEDED

Structure

Standard InChIKeyKQNZDYYTLMIZCT-QQRMDHKLSA-N
SMILES[H][C@@]12C[C@H](O)C[C@@]1([H])[C@@H](O)\C=C\C(=O)O[C@H](C)CCC\C=C\2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA018651

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Penicillium brefeldianum
NCBITaxon:1131482
BGC_CHARACTERIZED mibig:BGC0001141 DOI:10.1016/j.phytochem.2022.113243

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001141 Penicillium brefeldianum
NCBITaxon:1131482
CLUSTER_DEMONSTRATED genbank:KJ728786.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001141MIBIG4

This page is generated from data/natural_products/polyketides/4-epi-15-epi-brefeldin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.